serw-MX  [xml]  

 DeCS Categories

D02 Organic Chemicals .
D02.033 Alcohols .
D02.033.455 Glycols .
D02.033.455.706 Propylene Glycols .
D02.033.455.706.300 Chloramphenicol .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.559 Hydrocarbons, Aromatic .
D02.455.426.559.389 Benzene Derivatives .
D02.455.426.559.389.565 Nitrobenzenes .
D02.455.426.559.389.565.175 Chloramphenicol .
D02.640 Nitro Compounds .
D02.640.529 Nitrobenzenes .
D02.640.529.175 Chloramphenicol .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.913 Transferases .
D08.811.913.050 Acyltransferases .
D08.811.913.050.134 Acetyltransferases .
D08.811.913.050.134.170 Chloramphenicol O-Acetyltransferase .
G06 Microbiological Phenomena .
G06.099 Bacterial Physiological Phenomena .
G06.099.225 Drug Resistance, Bacterial .
G06.099.225.750 Chloramphenicol Resistance .
G06.225 Drug Resistance, Microbial .
G06.225.347 Drug Resistance, Bacterial .
G06.225.347.750 Chloramphenicol Resistance .
G07 Physiological Phenomena .
G07.690 Pharmacological and Toxicological Phenomena .
G07.690.773 Pharmacological Phenomena .
G07.690.773.984 Drug Resistance .
G07.690.773.984.269 Drug Resistance, Microbial .
G07.690.773.984.269.347 Drug Resistance, Bacterial .
G07.690.773.984.269.347.750 Chloramphenicol Resistance .
HP4 Materia Medica .
HP4.018 Homeopathic Remedy .
HP4.018.189 Homeopathic Remedy C .
HP4.018.189.469 Chloramphenicolum .
 Synonyms & Historicals
Chloramphenicol O-Acetyltransferase .
Chloramphenicol Transacetylase .
Acetyltransferase, Chloramphenicol .
Chloramphenicol O Acetyltransferase .
Enzyme, CAT .
O-Acetyltransferase, Chloramphenicol .
Transacetylase, Chloramphenicol .
CAT Enzyme .
Chloramphenicol Acetyltransferase .
An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC .
Chloramphenicol .
Chlornitromycin .
Chlorocid .
Chloromycetin .
Detreomycin .
Ophthochlor .
Syntomycin .
Cloranfenicol .
Kloramfenikol .
Levomycetin .
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) .
Chloramphenicolum .
Chloromycetinum .
Homeopathic remedy. Chloromycetinum. Abbrev.: "chloram.". Chemical origin. Substance used: chloramphenicol. .
Chloramphenicol Resistance .
Chloramphenicol Resistances .
Nonsusceptibility of bacteria to the action of CHLORAMPHENICOL, a potent inhibitor of protein synthesis in the 50S ribosomal subunit where amino acids are added to nascent bacterial polypeptides. .