serw-MX  [xml]  

 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.276 Intercellular Signaling Peptides and Proteins .
D12.644.276.374 Cytokines .
D12.644.276.374.480 Lymphokines .
D12.644.276.374.480.438 Lymphotoxin-alpha .
D12.644.276.374.500 Monokines .
D12.644.276.374.500.800 Tumor Necrosis Factor-alpha .
D12.644.276.374.750 Tumor Necrosis Factors .
D12.644.276.374.750.124 CD40 Ligand .
D12.644.276.374.750.155 Cytokine TWEAK .
D12.644.276.374.750.249 Fas Ligand Protein .
D12.644.276.374.750.500 Lymphotoxin-alpha .
D12.644.276.374.750.515 Lymphotoxin-beta .
D12.644.276.374.750.531 OX40 Ligand .
D12.644.276.374.750.625 TNF-Related Apoptosis-Inducing Ligand .
D12.644.276.374.750.626 Tumor Necrosis Factor-alpha .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.900 Tumor Necrosis Factor-alpha .
D12.776.395 Glycoproteins .
D12.776.395.550 Membrane Glycoproteins .
D12.776.395.550.185 CD40 Ligand .
D12.776.395.550.312 Fas Ligand Protein .
D12.776.395.550.597 OX40 Ligand .
D12.776.395.930 Tumor Necrosis Factor-alpha .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.374 Cytokines .
D12.776.467.374.480 Lymphokines .
D12.776.467.374.480.438 Lymphotoxin-alpha .
D12.776.467.374.500 Monokines .
D12.776.467.374.500.800 Tumor Necrosis Factor-alpha .
D12.776.467.374.750 Tumor Necrosis Factors .
D12.776.467.374.750.124 CD40 Ligand .
D12.776.467.374.750.155 Cytokine TWEAK .
D12.776.467.374.750.249 Fas Ligand Protein .
D12.776.467.374.750.500 Lymphotoxin-alpha .
D12.776.467.374.750.515 Lymphotoxin-beta .
D12.776.467.374.750.531 OX40 Ligand .
D12.776.467.374.750.625 TNF-Related Apoptosis-Inducing Ligand .
D12.776.467.374.750.626 Tumor Necrosis Factor-alpha .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.198 CD40 Ligand .
D12.776.543.550.312 Fas Ligand Protein .
D12.776.543.550.590 OX40 Ligand .
D23 Biological Factors .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.374 Cytokines .
D23.529.374.480 Lymphokines .
D23.529.374.480.438 Lymphotoxin-alpha .
D23.529.374.500 Monokines .
D23.529.374.500.800 Tumor Necrosis Factor-alpha .
D23.529.374.750 Tumor Necrosis Factors .
D23.529.374.750.124 CD40 Ligand .
D23.529.374.750.155 Cytokine TWEAK .
D23.529.374.750.249 Fas Ligand Protein .
D23.529.374.750.500 Lymphotoxin-alpha .
D23.529.374.750.515 Lymphotoxin-beta .
D23.529.374.750.531 OX40 Ligand .
D23.529.374.750.625 TNF-Related Apoptosis-Inducing Ligand .
D23.529.374.750.626 Tumor Necrosis Factor-alpha .
 Synonyms & Historicals
Tumor Necrosis Factors .
TNF Receptor Ligands .
Tumor Necrosis Factor Superfamily Ligands .
Necrosis Factors, Tumor .
Receptor Ligands, TNF .
TNF 26382 .
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. .
Lymphotoxin-alpha .
Lymphotoxin .
Lymphotoxin-alpha3 .
Soluble Lymphotoxin-alpha .
alpha-Lymphotoxin .
Lymphotoxin alpha .
Lymphotoxin alpha3 .
Lymphotoxin-alpha, Soluble .
Soluble Lymphotoxin alpha .
Tumor Necrosis Factor beta .
alpha Lymphotoxin .
TNF Superfamily, Member 1 .
TNF-beta .
Tumor Necrosis Factor-beta .
Tumor Necrosis Factor Ligand Superfamily Member 1 .
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR. .
Tumor Necrosis Factor-alpha .
Cachectin-Tumor Necrosis Factor .
TNF Superfamily, Member 2 .
TNFalpha .
Tumor Necrosis Factor .
Cachectin Tumor Necrosis Factor .
Tumor Necrosis Factor alpha .
Cachectin .
TNF-alpha .
Tumor Necrosis Factor Ligand Superfamily Member 2 .
Tumor Necrosis Factor .
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. .
Lymphotoxin-beta .
TNF Superfamily, Member 3 .
Tumor Necrosis Factor C .
beta, Lymphotoxin .
Lymphotoxin beta .
Tumor Necrosis Factor Ligand Superfamily Member 3 .
A membrane-bound tumor necrosis family member found primarily on LYMPHOCYTES. It can form a heterotrimer (LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER) with the soluble ligand LYMPHOTOXIN-ALPHA and anchor it to the cell surface. The membrane-bound complex is specific for the LYMPHOTOXIN BETA receptor. .
OX40 Ligand .
CD134 Ligand .
CD134L Protein .
OX40L Protein .
TNF Superfamily, Member 4 .
Tumor Necrosis Factor (Ligand) Superfamily, Member 4 .
gp34 Tumor Necrosis Factor .
Tumor Necrosis Factor Ligand Superfamily Member 4 .
A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-LYMPHOCYTES and MACROPHAGES. It signals T-LYMPHOCYTES by binding the OX40 RECEPTOR. .
CD40 Ligand .
Antigen, CD154 .
CD154 Antigen .
CD40L .
T-B Cell Activating Molecule .
TNF Superfamily, Member 5 .
gp39 Antigen, T-Cell .
T-Cell gp39 Antigen .
gp39 Antigen, T Cell .
Antigens, CD154 .
CD154 Antigens .
Tumor Necrosis Factor Ligand Superfamily Member 5 .
A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1. .
TNF-Related Apoptosis-Inducing Ligand .
Apo-2 Ligand .
Apo-2L Protein .
CD253 Antigen .
TNF Superfamily, Member 10 .
TRAIL Protein .
Antigen, CD253 .
Apo 2 Ligand .
Apo 2L Protein .
Apoptosis-Inducing Ligand, TNF-Related .
TNF Related Apoptosis Inducing Ligand .
Tumor Necrosis Factor Ligand Superfamily Member 10 .
A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form. .
Fas Ligand Protein .
CD178 Antigen .
CD95 Antigen Ligand .
CD95 Ligand .
CD95L .
Fas Ligand .
Fas Ligand (FasL) .
FasL Protein .
TNF Superfamily, Member 6 .
Antigen, CD178 .
Antigens, CD178 .
CD178 Antigens .
Tumor Necrosis Factor Ligand Superfamily Member 6 .
A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS. .
Cytokine TWEAK .
Apo3 Ligand .
TNF-Related Weak Inducer of Apoptosis .
TWEAK Cytokine .
Tumor Necrosis Factor Ligand Superfamily Member 12 .
Cytokine, TWEAK .
Ligand, Apo3 .
TNF Related Weak Inducer of Apoptosis .
TWEAK, Cytokine .
A proteolytically-cleaved membrane glycoprotein and member of the TNF superfamily that is highly expressed in a variety of tissues including heart, pancreas, brain, and peripheral blood lymphocytes. The secreted extracellular form is a weak inducer of APOPTOSIS for some cell types and a ligand for the FN14 RECEPTOR. It mediates activation of NF-KAPPA-B and promotes ANGIOGENESIS and proliferation of ENDOTHELIAL CELLS, as well as expression of cytokines involved in INFLAMMATION. .