serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.656 Peptide Hydrolases .
D08.811.277.656.675 Metalloproteases .
D08.811.277.656.675.374 Metalloendopeptidases .
D08.811.277.656.675.374.102 ADAM Proteins .
D08.811.277.656.675.374.102.375 ADAM17 Protein .
D09 Carbohydrates .
D09.400 Glycoconjugates .
D09.400.430 Glycoproteins .
D09.400.430.500 ADAM Proteins .
D09.400.430.500.375 ADAM17 Protein .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.276 Intercellular Signaling Peptides and Proteins .
D12.644.276.374 Cytokines .
D12.644.276.374.480 Lymphokines .
D12.644.276.374.480.438 Lymphotoxin-alpha .
D12.644.276.374.500 Monokines .
D12.644.276.374.500.800 Tumor Necrosis Factor-alpha .
D12.644.276.374.750 Tumor Necrosis Factors .
D12.644.276.374.750.500 Lymphotoxin-alpha .
D12.644.276.374.750.515 Lymphotoxin-beta .
D12.644.276.374.750.626 Tumor Necrosis Factor-alpha .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.900 Tumor Necrosis Factor-alpha .
D12.776.395 Glycoproteins .
D12.776.395.033 ADAM Proteins .
D12.776.395.033.375 ADAM17 Protein .
D12.776.395.930 Tumor Necrosis Factor-alpha .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.374 Cytokines .
D12.776.467.374.480 Lymphokines .
D12.776.467.374.480.438 Lymphotoxin-alpha .
D12.776.467.374.500 Monokines .
D12.776.467.374.500.800 Tumor Necrosis Factor-alpha .
D12.776.467.374.750 Tumor Necrosis Factors .
D12.776.467.374.750.500 Lymphotoxin-alpha .
D12.776.467.374.750.515 Lymphotoxin-beta .
D12.776.467.374.750.626 Tumor Necrosis Factor-alpha .
D23 Biological Factors .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.374 Cytokines .
D23.529.374.480 Lymphokines .
D23.529.374.480.438 Lymphotoxin-alpha .
D23.529.374.500 Monokines .
D23.529.374.500.800 Tumor Necrosis Factor-alpha .
D23.529.374.750 Tumor Necrosis Factors .
D23.529.374.750.500 Lymphotoxin-alpha .
D23.529.374.750.515 Lymphotoxin-beta .
D23.529.374.750.626 Tumor Necrosis Factor-alpha .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Tumor Necrosis Factor-alpha .
Cachectin-Tumor Necrosis Factor .
TNF Superfamily, Member 2 .
TNFalpha .
Tumor Necrosis Factor .
Cachectin Tumor Necrosis Factor .
Tumor Necrosis Factor alpha .
Cachectin .
TNF-alpha .
Tumor Necrosis Factor Ligand Superfamily Member 2 .
Tumor Necrosis Factor .
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. .
1.00
737111894
 
Tumor Necrosis Factors .
TNF Receptor Ligands .
Tumor Necrosis Factor Superfamily Ligands .
Necrosis Factors, Tumor .
Receptor Ligands, TNF .
TNF 26382 .
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. .
0.87
452038
 
ADAM17 Protein .
ADAM-17 .
ADAM-17 Protein .
CD156b Antigen .
Disintegrin and Metalloproteinase Domain-Containing Protein 17 .
TACA (Enzyme) .
TACE (Enzyme) .
TNF-alpha Convertase .
TNF-alpha Converting Enzyme .
Tumor Necrosis Factor Alpha Convertase .
Tumor Necrosis Factor-alpha Convertase .
Tumor Necrosis Factor-alpha Converting Enzyme .
ADAM 17 Protein .
Antigen, CD156b .
Convertase, TNF-alpha .
Disintegrin and Metalloproteinase Domain Containing Protein 17 .
TNF alpha Convertase .
TNF alpha Converting Enzyme .
Tumor Necrosis Factor alpha Converting Enzyme .
A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS. .
0.86
01469
 
Lymphotoxin-beta .
TNF Superfamily, Member 3 .
Tumor Necrosis Factor C .
beta, Lymphotoxin .
Lymphotoxin beta .
Tumor Necrosis Factor Ligand Superfamily Member 3 .
A membrane-bound tumor necrosis family member found primarily on LYMPHOCYTES. It can form a heterotrimer (LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER) with the soluble ligand LYMPHOTOXIN-ALPHA and anchor it to the cell surface. The membrane-bound complex is specific for the LYMPHOTOXIN BETA receptor. .
0.80
0212
 
Lymphotoxin-alpha .
Lymphotoxin .
Lymphotoxin-alpha3 .
Soluble Lymphotoxin-alpha .
alpha-Lymphotoxin .
Lymphotoxin alpha .
Lymphotoxin alpha3 .
Lymphotoxin-alpha, Soluble .
Soluble Lymphotoxin alpha .
Tumor Necrosis Factor beta .
alpha Lymphotoxin .
TNF Superfamily, Member 1 .
TNF-beta .
Tumor Necrosis Factor-beta .
Tumor Necrosis Factor Ligand Superfamily Member 1 .
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR. .
0.80
232872