serw-MX  [xml]  

 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.399 Isomerases .
D08.811.399.403 DNA Topoisomerases .
D08.811.399.403.741 DNA Topoisomerases, Type II .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.892 Topoisomerase Inhibitors .
D27.505.519.389.892.750 Topoisomerase II Inhibitors .
D27.505.954 Therapeutic Uses .
D27.505.954.248 Antineoplastic Agents .
D27.505.954.248.794 Topoisomerase Inhibitors .
D27.505.954.248.794.750 Topoisomerase II Inhibitors .
 Synonyms & Historicals
DNA Topoisomerases, Type II .
DNA Topoisomerase II alpha .
DNA Topoisomerase II beta .
DNA Type 2 Topoisomerase .
TOP2A Protein .
TOP2B Protein .
Topoisomerase II .
Topoisomerase II alpha .
Topoisomerase II beta .
Type II DNA Topoisomerase .
alpha, Topoisomerase II .
beta, Topoisomerase II .
DNA Topoisomerase (ATP-Hydrolysing) .
DNA Topoisomerase II .
DNA Topoisomerases, Type II, Eukaryotic .
DNA Topoisomerases, Type II, Bacterial .
DNA Topoisomerase II, Bacterial .
DNA Topoisomerases, Type II, Archaeal .
DNA TOPOISOMERASES that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex. .
Topoisomerase II Inhibitors .
DNA Gyrase Inhibitors .
DNA Topoisomerase II Inhibitors .
DNA Type 2 Topoisomerase Inhibitors .
Gyrase Inhibitors, DNA .
Inhibitors, DNA Gyrase .
Inhibitors, Topoisomerase 2 .
Inhibitors, Topoisomerase II .
Topoisomerase 2 Inhibitors .
Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. .