serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.065 Amides .
D02.065.589 Lactams .
D02.065.589.099 beta-Lactams .
D02.886 Sulfur Compounds .
D02.886.108 beta-Lactams .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.411 Lactams .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.300 beta-Lactams .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.087 Amidohydrolases .
D08.811.277.087.180 beta-Lactamases .
D08.811.277.087.180.229 Cephalosporinase .
D08.811.277.087.180.697 Penicillinase .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
beta-Lactams .
4-Thia-1-Azabicyclo(3.2.0)Heptanes .
4-Thia-1-Azabicyclo(4.2.0)Octanes .
beta Lactams .
Antibiotics, beta-Lactam .
beta-Lactam Antibiotics .
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria. .
1.00
455858
 
beta-Lactamases .
beta-Lactamase .
beta Lactamase .
beta Lactamases .
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins. .
0.87
 
Lactams .
Lactims .
Antibiotics, Lactam .
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams. .
0.78
1253770
 
Penicillinase .
AER-I beta-Lactamase .
Benzylpenicillinase .
Carbenicillinase .
Exopenicillinase .
beta Lactamase III .
beta Lactamase RP4 .
gamma-Penicillinase .
AER I beta Lactamase .
Lactamase RP4, beta .
beta Lactamase I .
beta-Lactamase, AER-I .
gamma Penicillinase .
beta-Lactamase I .
A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-. .
0.75
402189
 
Cephalosporinase .
Cephalexin Amidase .
Cephalosporin Amido-beta-Lactam Hydrolase .
Cephalosporin beta-Lactamase .
Amidase, Cephalexin .
Amido-beta-Lactam Hydrolase, Cephalosporin .
Cephalosporin Amido beta Lactam Hydrolase .
Cephalosporin beta Lactamase .
Hydrolase, Cephalosporin Amido-beta-Lactam .
beta Lactamase II .
beta-Lactamase, Cephalosporin .
beta-Lactamase II .
0.74
7507