Baculoviral IAP Repeat-Containing 3 Protein. Apoptosis Inhibitor 2 . BIRC3 Protein . Baculoviral IAP Repeat Containing Protein 3 . Cellular Inhibitor of Apoptosis-2 . Hiap-1 Protein . IAP1 Protein . Inhibitor of Apoptosis 1 Protein . Inhibitor of Apoptosis Protein 1 . c-IAP2 Protein . cIAP2 Protein . Apoptosis-2 Cellular Inhibitor . Baculoviral IAP Repeat Containing 3 Protein . Cellular Inhibitor of Apoptosis 2 . Hiap 1 Protein . Inhibitor 2, Apoptosis . A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells. . 1.00
Inhibitor of Apoptosis Proteins. BIRC2 Protein . Baculoviral IAP Repeat Containing Protein 2 . Baculoviral IAP Repeat-Containing 2 Protein . Baculoviral Inhibitor Of Apoptosis Repeat Proteins . Cellular Inhibitor of Apoptosis 1 Protein . IAP Protein (Apoptosis) . IAP Repeat Containing Proteins . IAP2 Protein . Inhibitor of Apoptosis 2 Protein . Inhibitor-Of-Apoptosis Protein . c-IAP1 Protein . cIAP1 Protein . Apoptosis Proteins Inhibitor . Baculoviral IAP Repeat Containing 2 Protein . Inhibitor Of Apoptosis Protein . A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity. . 0.87
Tadalafil. Cialis . IC 351 . IC-351 . IC351 . 351, IC . A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION. . 0.57
Proteins. Protein Gene Products . Proteins, Gene . Gene Proteins . Gene Products, Protein . GENE PRODUCTS . Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. . 0.49
Neural Cell Adhesion Molecule L1. CALL Protein . CamL1 Gene Product . Cell Adhesion Molecule L1 . Cell Surface Glycoprotein L1 . F11 Glycoprotein . L1 Cell Adhesion Molecule . L1CAM . NGF-Inducible Glycoprotein . NILE Glycoprotein . NILE Protein . Nerve Growth Factor-Inducible Large External Glycoprotein . Neural Adhesion Molecule L1 . Glycoprotein, NGF-Inducible . Glycoprotein, NILE . NGF Inducible Glycoprotein . Nerve Growth Factor Inducible Large External Glycoprotein . A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for proper nervous system development. Neural cell adhesion molecule L1 consists of six Ig domains, five fibronectin domains, a transmembrane region and an intracellular domain. Two splicing variants are known: a neuronal form that contains a four-amino acid RSLE sequence in the cytoplasmic domain, and a non-neuronal form that lacks the RSLE sequence. Mutations in the L1 gene result in L1 disease. Neural cell adhesion molecule L1 is predominantly expressed during development in neurons and Schwann cells; involved in cell adhesion, neuronal migration, axonal growth and pathfinding, and myelination. . 0.46
ATP Binding Cassette Transporter 1. ABCA1 Protein . ATP-Binding Cassette Sub-Family A Member 1 . CERP Protein . Cholesterol-Efflux Regulatory Protein . ATP Binding Cassette Sub Family A Member 1 . Cholesterol Efflux Regulatory Protein . Protein, ABCA1 . Protein, CERP . Protein, Cholesterol-Efflux Regulatory . Regulatory Protein, Cholesterol-Efflux . A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues. . 0.44
