Sialic Acid Binding Ig-like Lectin 3. Antigens, CD33 . CD33 Antigen . CD33 Antigens . Glycoprotein gp67 . Siglec-3 . Antigen, CD33 . Sialic Acid Binding Ig like Lectin 3 . gp67, Glycoprotein . A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE. . 1.00
ATP-Binding Cassette, Sub-Family B, Member 1. ABCB1 Protein . CD243 Antigen . PGY-1 Protein . Antigen, CD243 . P Glycoprotein . PGY 1 Protein . MDR1 Protein . Multidrug Resistance Protein 1 . P-Glycoprotein . MULTIDRUG TRANSPORTER . A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). . 0.57
Contactin 1. Glycoprotein gp135 . Neural Cell Surface Protein F3 . gp135, Glycoprotein . A contactin subtype that is predominantly expressed in the CEREBELLUM; HIPPOCAMPUS; NEOCORTEX; and HYPOTHALAMUS. . 0.56
ATP Binding Cassette Transporter, Sub-Family B. ATP-Binding Cassette, Sub-Family B Proteins . ATP Binding Cassette Transporter, Sub Family B . ATP Binding Cassette, Sub Family B Proteins . P Glycoproteins . P-Glycoproteins . Multidrug Resistance Proteins . A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY B share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology. . 0.56