serw-MX [xml]
 
 


 
check
 

0.52 /METABOLISMO . 
0.12 CORTICOSTERONA .
0.12 11-BETA-HIDROXIESTEROIDE DESIDROGENASE TIPO 2 .
0.12 /FISIOLOGIA .
0.11 /COMPLICACOES .

Rank Sim. Fonte Título, abstract e conceitos DeCS   Conceitos DeCS em LILACS 
1 0.43 LILACS Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer . 
ALDEIDO DESIDROGENASE; /METABOLISMO; FATORES DE TRANSCRICAO HELICE-ALCA-HELICE BASICOS; /METABOLISMO; NEOPLASIAS DA MAMA; /METABOLISMO; FATOR 1 INDUZIVEL POR HIPOXIA; /METABOLISMO .
OBJECTIVE: To analyze the expression of hypoxia-inducible factors (hypoxia-inducible factor 1A and hypoxia-inducible factor 2A) and aldehyde dehydrogenase proteins in patients with locally advanced breast carcinoma who were subjected to neoadjuvant chemotherapy METHODS: We included 90 patients with histologically confirmed stage II and III breast carcinoma who were treated with neoadjuvant chemo .. uced overall survival CONCLUSION: The presence of aldehyde dehydrogenase-positive cells within the residual tumor after neoadjuvant chemotherapy is associated with an increase in the expression (AU) .
  0.64 /METABOLISMO . 
0.14 NEOPLASIAS DA MAMA .
0.08 FATOR 1 INDUZIVEL POR HIPOXIA .
0.08 ALDEIDO DESIDROGENASE .
0.06 FATORES DE TRANSCRICAO HELICE-ALCA-HELICE BASICOS .
2 0.41 LILACS Sperm especific lactate dehydrogenase . 

  0.42 L-LACTATO DESIDROGENASE . 
0.30 ESPERMATOZOIDES .
0.10 ANDROGENIOS .
0.09 UROLOGIA .
0.08 ACIDO OXAMICO .
3 0.38 LILACS MDCK cells express serotonin-regulable 11beta-hydroxysteroiddehydrogenase type 2 . 
11-BETA-HIDROXIESTEROIDE DESIDROGENASE TIPO 2; /METABOLISMO; CORTICOSTERONA; /ANALOGOS & DERIVADOS; CORTICOSTERONA; /METABOLISMO; ATIVACAO ENZIMATICA; /EFEITOS DE DROGAS; SEROTONINA; /FARMACOLOGIA .
Prior to this work, we found that adrenal as well as extra-adrenal factors activate the response of renal 11beta-hydroxysteroid dehydrogenase 2 to stressful situations These results -showing ways through which the organism hinders the pathological occupation of mineralocorticoid receptors by glucocorticoids leading to sodium retention and hypertension- prompted the present study on the nature of t .. lation of the 11beta-hydroxysteroid dehydrogenase 2 activity Given many, mostly positive, interactions between both hormones, this might eventually pave the way to studies on a new regulatory axis(AU) .

  0.28 /METABOLISMO . 
0.21 /EFEITOS DE DROGAS .
0.21 /ENZIMOLOGIA .
0.15 /FARMACOLOGIA .
0.14 CORTICOSTERONA .
4 0.36 LILACS Role of 11â-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure . 
11-BETA-HIDROXIESTEROIDE DESIDROGENASE TIPO 2; /FISIOLOGIA; HOMEOSTASE; /FISIOLOGIA; FALENCIA RENAL CRONICA; /METABOLISMO; MICROSSOMOS; /ENZIMOLOGIA; POTASSIO; /METABOLISMO .
Aldosterone concentrations vary in advanced chronic renal failure (CRF) The isozyme 11â-hydroxysteroid dehydrogenase 2 (11â-HSD2), which confers aldosterone specificity for mineralocorticoid receptors in distal tubules and collecting ducts, has been reported to be decreased or normal in patients with renal diseases Our objective was to determine the role of aldosterone and 11â-HSD2 renal microsome .. s lower in CRF rats (sham = 0807 ± 009 and CRF = 0217 ± 007 nmolÀmin-1Àmg protein-1; P < 005), although when normalized for mL GFR it was similar in both groups We conclude that K+ homeostasis is (AU) .

  0.32 /METABOLISMO . 
0.27 /ENZIMOLOGIA .
0.18 /FISIOLOGIA .
0.13 11-BETA-HIDROXIESTEROIDE DESIDROGENASE TIPO 2 .
0.11 /COMPLICACOES .
5 0.35 LILACS Hyperandrogenism due to 3 beta-hydroxysteroid dehydrogenase deficiency with accessory adrenocortical tissue: a hormonal and metabolic evaluation . 
3-HIDROXIESTEROIDE DESIDROGENASES; /DEFICIENCIA; TUMOR DE RESTO SUPRARRENAL; /COMPLICACOES; HIPERANDROGENISMO; /ETIOLOGIA; NEOPLASIAS OVARIANAS; /COMPLICACOES .
1 Adrenal ectopic tissue has been detected in the paragonadal region of normal women In patients with congenital adrenal hyperplasia due to 21-hydroxylase (21-OH) deficiency, the manifestation of hyperplasia of paragonadal accessory adrenal tissue has been usually reported to occur in males Probably, this is the first report of a female with 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficie .. lower than that of 14 normal women (area under the curve, 3 beta-HSD = 17,680 vs 50,034 pmol/l for the control group over a period of 3 h after glucose ingestion)(ABSTRACT TRUNCATED AT 250 WORDS)(Au) .

  0.30 /DEFICIENCIA . 
0.18 3-HIDROXIESTEROIDE DESIDROGENASES .
0.18 /METABOLISMO .
0.17 /COMPLICACOES .
0.17 /ENZIMOLOGIA .
6 0.35 LILACS Effect of the ionic environment on the activity of the mitochondrial L-malate dehydrogenase . 

  0.25 ASPARAGINA . 
0.25 GLUTAMATO DESIDROGENASE .
0.17 L-LACTATO DESIDROGENASE .
0.16 MALATO DESIDROGENASE .
0.16 CONCENTRACAO OSMOLAR .
7 0.35 LILACS The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthora perniciosa, the causal agent of witches' broom disease of Theobroma cacao . 
This report describes the cloning, sequence and expression analysis of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene of Moniliophthora perniciosa, the most important pathogen of cocoa in Brazil Southern blot analysis revealed the presence of a single copy of the GAPDH gene in the M perniciosa genome (MpGAPDH) The complete MpGAPDH coding sequence contained 1,461 bp with eight introns th .. APDH gene by real-time PCR showed that this gene was more expressed (~13X) in the saprotrophic stage of this hemibiotrophic plant pathogen than in the biotrophic stage when grown in cacao extracts(AU) .

  0.29 /GENETICA . 
0.27 /QUIMICA .
0.15 PLANTAS .
0.15 GLICOLISE .
0.14 INOSINA MONOFOSFATO .
8 0.35 LILACS Evidence in Colombia of 625G>A polymorphism in the short chain acyl-CoA dehydrogenase gene, a variation which could cause glutaric aciduria in our populations . 
ACIL-COA DESIDROGENASE; POLIMORFISMO GENETICO; /GENETICA; OXIDACAO; /EFEITOS ADVERSOS .
Introduction: Short-chain acyl-CoA dehydrogenase (SCAD) is a homotetrameric mitochondrial flavoenzyme that catalyzes the initial reaction in short-chain fatty acid b-oxidation The SCAD gene is located on chromosome 12q22 and is approximately 13 kb long with 10 exons and 1236 nucleotides of coding sequence Hereditary SCAD deficiency has been reported and only a few cases of this disorder have been .. he short-chain acyl-CoA dehydrogenase gene in Colombia, meaning that some people in our populations can be at risk of suffering SCAD deficiency and its main complication: the ethylmalonic aciduria(AU) .

  0.28 /GENETICA . 
0.22 POLIMORFISMO GENETICO .
0.17 OXIDACAO .
0.17 /EFEITOS ADVERSOS .
0.17 ACIL-COA DESIDROGENASE .
9 0.34 LILACS Generation of reduced nicotinamide adenine dinucleotide phosphate mediated by glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in neutrophils of thoroughbred horses . 
Em vinte cavalos Puro-Sangue Inglês determinou-se a atividade da glicose-6-fosfato-desidrogenase e da 6-fosfogliconato-desidrogenase de neutrófilos, encontrando-se atividades específicas de 945 ñ 288 mUI mg-1 de proteína e 375 ñ 88 mUI mg-1 de proteína, respectivamente, por minuto a 37§C (AU) .

  0.22 /SANGUE . 
0.21 DEFICIENCIA DE GLUCOSEFOSFATO DESIDROGENASE .
0.20 /ENZIMOLOGIA .
0.19 GLUCOSEFOSFATO DESIDROGENASE .
0.18 /METABOLISMO .
10 0.34 LILACS Novel antiviral activity of dialdehyde starch . 
AMIDO; /ANALISE; AMIDO; /USO TERAPEUTICO; ALDEIDOS; /ANALISE; ALDEIDOS; /USO TERAPEUTICO; PRAGUICIDAS; /SINTESE QUIMICA .
A significant effort worldwide is being directed toward development of novel biocides against drug-resistant bacterial and viruses because of the significant potential human infection risks in the general population We report here the discovery of a strong antiviral biocide, dialdheyde starch (DAS) Antiviral tests were carried out against three non-envelop viruses, including two bacterial viruses .. and four-order reduction against Poliovirus The antiviral activity of dialdehyde starch was found to be pH dependent, being more active in alkaline and acidic conditions than in neutral conditions(AU) .

  0.44 /USO TERAPEUTICO . 
0.17 ALDEIDOS .
0.15 /ANALISE .
0.12 ANTIVIRAIS .
0.11 AMIDO .