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0.52 /METABOLISMO . 
0.12 /QUIMICA .
0.12 CORTICOSTERONA .
0.12 11-BETA-HIDROXIESTEROIDE DESIDROGENASE TIPO 2 .
0.12 /FISIOLOGIA .

Rank Sim. Fonte Título, abstract e conceitos DeCS   Conceitos DeCS em LILACS 
1 0.59 LILACS Increased salivary aldehyde dehydrogenase 1 in non-reticular oral lichen planus^ien . 
ehydrogenase may be one of the malignant transformation markers in oral lichen planus Further studies are needed for introducing aldehyde dehydrogenase as a prognostic indicator in certain lesions^ien] + Increased salivary aldehyde dehydrogenase 1 in non-reticular oral lichen planus^ien; An bras dermatol .
Abstract: Background: Oral lichen planus is a potentially malignant disorder One of the malignant transformation markers is cancer stem cells One of the proposed marker for the detection of cancer stem cells's in head and neck cancer is aldehyde dehydrogenase Recently it is shown that aldehyde dehydrogenase 1 expression in tissue samples is associated with oral lichen planus malignant transformat .. ehydrogenase may be one of the malignant transformation markers in oral lichen planus Further studies are needed for introducing aldehyde dehydrogenase as a prognostic indicator in certain lesions^ien .
  0.21 /PATOLOGIA . 
0.21 NEOPLASIAS BUCAIS .
0.21 LIQUEN PLANO BUCAL .
0.20 /QUIMICA .
0.18 /FARMACOLOGIA .
2 0.43 LILACS Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer^ien . 
[OBJECTIVE: To analyze the expression of hypoxia-inducible factors (hypoxia-inducible factor 1A and hypoxia-inducible factor 2A) and aldehyde dehydrogenase proteins in patients with locally advanced breast carcinoma who were subjected to neoadjuvant chemotherapy METHODS: We included 90 patients with histologically confirmed stage II and III breast carcinoma who were treated with neoadjuvant chemoth .
OBJECTIVE: To analyze the expression of hypoxia-inducible factors (hypoxia-inducible factor 1A and hypoxia-inducible factor 2A) and aldehyde dehydrogenase proteins in patients with locally advanced breast carcinoma who were subjected to neoadjuvant chemotherapy METHODS: We included 90 patients with histologically confirmed stage II and III breast carcinoma who were treated with neoadjuvant chemoth .. educed overall survival CONCLUSION: The presence of aldehyde dehydrogenase-positive cells within the residual tumor after neoadjuvant chemotherapy is associated with an increase in the expression ^ien .

  0.66 /METABOLISMO . 
0.13 NEOPLASIAS DA MAMA .
0.08 FATOR 1 INDUZIVEL POR HIPOXIA .
0.08 ALDEIDO DESIDROGENASE .
0.06 FATORES DE TRANSCRICAO HELICE-ALCA-HELICE BASICOS .
3 0.40 LILACS Sperm especific lactate dehydrogenase^ien . 

  0.65 L-LACTATO DESIDROGENASE . 
0.16 ESPERMATOZOIDES .
0.06 LACTATO DESIDROGENASES .
0.06 ACIDO OXAMICO .
0.06 ELECTROPHORUS .
4 0.39 LILACS Relationship between acetaldehyde concentration in mouth air and tongue coating volume^ien . 
[Objective Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species However, it is uncertain whether acetaldehyde concentration in human breath is related to oral condition or local production of acetaldehyde by oral microflora The aim of this pilo .
Objective Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species However, it is uncertain whether acetaldehyde concentration in human breath is related to oral condition or local production of acetaldehyde by oral microflora The aim of this pilo .. clinical parameters, presence of Candida species, smoking status or alcohol sensitivity Conclusion Physiological acetaldehyde concentration in mouth air was associated with tongue coating volume ^ien .

  0.36 /QUIMICA . 
0.19 /ANALISE .
0.19 /METABOLISMO .
0.13 ACETALDEIDO .
0.13 LINGUA .
5 0.38 LILACS MDCK cells express serotonin-regulable 11beta-hydroxysteroiddehydrogenase type 2^ien . 
[Prior to this work, we found that adrenal as well as extra-adrenal factors activate the response of renal 11beta-hydroxysteroid dehydrogenase 2 to stressful situations These results -showing ways through which the organism hinders the pathological occupation of mineralocorticoid receptors by glucocorticoids leading to sodium retention and hypertension- prompted the present study on the nature of t .
Prior to this work, we found that adrenal as well as extra-adrenal factors activate the response of renal 11beta-hydroxysteroid dehydrogenase 2 to stressful situations These results -showing ways through which the organism hinders the pathological occupation of mineralocorticoid receptors by glucocorticoids leading to sodium retention and hypertension- prompted the present study on the nature of t .. lation of the 11beta-hydroxysteroid dehydrogenase 2 activity Given many, mostly positive, interactions between both hormones, this might eventually pave the way to studies on a new regulatory axis^ien .

  0.29 /METABOLISMO . 
0.21 /EFEITOS DE DROGAS .
0.21 /ENZIMOLOGIA .
0.15 /FARMACOLOGIA .
0.14 CORTICOSTERONA .
6 0.36 LILACS Role of 11â-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure^ien . 
[Aldosterone concentrations vary in advanced chronic renal failure (CRF) The isozyme 11â-hydroxysteroid dehydrogenase 2 (11â-HSD2), which confers aldosterone specificity for mineralocorticoid receptors in distal tubules and collecting ducts, has been reported to be decreased or normal in patients with renal diseases Our objective was to determine the role of aldosterone and 11â-HSD2 renal microsome .
Aldosterone concentrations vary in advanced chronic renal failure (CRF) The isozyme 11â-hydroxysteroid dehydrogenase 2 (11â-HSD2), which confers aldosterone specificity for mineralocorticoid receptors in distal tubules and collecting ducts, has been reported to be decreased or normal in patients with renal diseases Our objective was to determine the role of aldosterone and 11â-HSD2 renal microsome .. s lower in CRF rats (sham = 0807 ± 009 and CRF = 0217 ± 007 nmol·min-1·mg protein-1; P < 005), although when normalized for mL GFR it was similar in both groups We conclude that K+ homeostasis is ^ien .

  0.32 /METABOLISMO . 
0.27 /ENZIMOLOGIA .
0.18 /FISIOLOGIA .
0.13 11-BETA-HIDROXIESTEROIDE DESIDROGENASE TIPO 2 .
0.11 /COMPLICACOES .
7 0.36 LILACS Generation of reduced nicotinamide adenine dinucleotide phosphate mediated by glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in neutrophils of thoroughbred horses^ien . 
[Em vinte cavalos Puro-Sangue Inglês determinou-se a atividade da glicose-6-fosfato-desidrogenase e da 6-fosfogliconato-desidrogenase de neutrófilos, encontrando-se atividades específicas de 945 ñ 288 mUI mg-1 de proteína e 375 ñ 88 mUI mg-1 de proteína, respectivamente, por minuto a 37§C ^ipt] + Generation of reduced nicotinamide adenine dinucleotide phosphate mediated by glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in neutrophils of thoroughbred horses^ien; Braz j vet res anim sci .
Em vinte cavalos Puro-Sangue Inglês determinou-se a atividade da glicose-6-fosfato-desidrogenase e da 6-fosfogliconato-desidrogenase de neutrófilos, encontrando-se atividades específicas de 945 ñ 288 mUI mg-1 de proteína e 375 ñ 88 mUI mg-1 de proteína, respectivamente, por minuto a 37§C ^ipt .

  0.22 GLUCOSEFOSFATO DESIDROGENASE . 
0.21 /SANGUE .
0.20 DEFICIENCIA DE GLUCOSEFOSFATO DESIDROGENASE .
0.19 /ENZIMOLOGIA .
0.18 /METABOLISMO .
8 0.35 LILACS Hyperandrogenism due to 3 beta-hydroxysteroid dehydrogenase deficiency with accessory adrenocortical tissue: a hormonal and metabolic evaluation^ien . 
[1 Adrenal ectopic tissue has been detected in the paragonadal region of normal women In patients with congenital adrenal hyperplasia due to 21-hydroxylase (21-OH) deficiency, the manifestation of hyperplasia of paragonadal accessory adrenal tissue has been usually reported to occur in males Probably, this is the first report of a female with 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficie .
1 Adrenal ectopic tissue has been detected in the paragonadal region of normal women In patients with congenital adrenal hyperplasia due to 21-hydroxylase (21-OH) deficiency, the manifestation of hyperplasia of paragonadal accessory adrenal tissue has been usually reported to occur in males Probably, this is the first report of a female with 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficie .. lower than that of 14 normal women (area under the curve, 3 beta-HSD = 17,680 vs 50,034 pmol/l for the control group over a period of 3 h after glucose ingestion)(ABSTRACT TRUNCATED AT 250 WORDS)^ien .

  0.31 /DEFICIENCIA . 
0.19 3-HIDROXIESTEROIDE DESIDROGENASES .
0.18 /COMPLICACOES .
0.18 /METABOLISMO .
0.14 /DIAGNOSTICO .
9 0.35 LILACS Effect of the ionic environment on the activity of the mitochondrial L-malate dehydrogenase^ien . 

  0.25 ASPARAGINA . 
0.25 GLUTAMATO DESIDROGENASE .
0.17 L-LACTATO DESIDROGENASE .
0.16 MALATO DESIDROGENASE .
0.16 CONCENTRACAO OSMOLAR .
10 0.35 LILACS The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthora perniciosa, the causal agent of witches' broom disease of Theobroma cacao^ien . 
APDH gene by real-time PCR showed that this gene was more expressed (~13X) in the saprotrophic stage of this hemibiotrophic plant pathogen than in the biotrophic stage when grown in cacao extracts^ien] + The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthora perniciosa, the causal agent of witches' broom disease of Theobroma cacao^ien; Genet mol biol .
This report describes the cloning, sequence and expression analysis of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene of Moniliophthora perniciosa, the most important pathogen of cocoa in Brazil Southern blot analysis revealed the presence of a single copy of the GAPDH gene in the M perniciosa genome (MpGAPDH) The complete MpGAPDH coding sequence contained 1,461 bp with eight introns th .. APDH gene by real-time PCR showed that this gene was more expressed (~13X) in the saprotrophic stage of this hemibiotrophic plant pathogen than in the biotrophic stage when grown in cacao extracts^ien .

  0.29 /GENETICA . 
0.27 /QUIMICA .
0.15 PLANTAS .
0.15 GLICOLISE .
0.14 INOSINA MONOFOSFATO .