serw-MX  [xml]  
 


    
 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.486 Immunoproteins .
D12.776.124.486.274 Complement System Proteins .
D12.776.124.486.274.045 Complement Activating Enzymes .
D12.776.124.486.274.045.387 Complement C3-C5 Convertases .
D12.776.124.486.274.045.387.750 Complement C3-C5 Convertases, Classical Pathway .
D12.776.124.486.274.045.387.750.500 Complement C3 Convertase, Classical Pathway .
D12.776.124.486.274.045.387.750.750 Complement C5 Convertase, Classical Pathway .
D12.776.124.486.274.150 Complement C2 .
D12.776.124.486.274.150.500 Complement C2a .
D12.776.124.486.274.350 Complement C4 .
D12.776.124.486.274.350.260 Complement C4b .
D12.776.124.486.274.920 Complement Inactivator Proteins .
D12.776.124.486.274.920.662 Complement C4b-Binding Protein .
G12 Immune System Phenomena .
G12.274 Complement Activation .
G12.274.698 Complement Pathway, Classical .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Complement C2 .
C2 Complement .
Complement 2 .
Complement Component 2 .
C2, Complement .
Complement, C2 .
Component 2, Complement .
Complement 2 .
A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE). .
1.00
51083
 
Complement C2a .
C2a Complement .
Complement 2a .
Complement C2 Fragment a .
Complement C2a Fragment .
C2a Fragment, Complement .
C2a, Complement .
Complement, C2a .
The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE). .
0.82
016
 
Complement C4b .
C4b Complement .
Complement 4b .
Complement Component 4b .
C4b, Complement .
Complement, C4b .
Component 4b, Complement .
Complement 4b .
The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE). .
0.78
21323
 
Complement Pathway, Classical .
Classical Complement Activation Pathway .
Complement Activation Pathway, Classical .
Classical Complement Pathway .
Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the sequential activation of COMPLEMENT C1R and COMPLEMENT C1S subunits. Activated C1s cleaves COMPLEMENT C4 and COMPLEMENT C2 forming the membrane-bound classical C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and the assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX. .
0.68
191785
 
Complement C3 Convertase, Classical Pathway .
C3 Convertase (C4b2a) .
Classical C3 Convertase .
Classical Pathway C3 Convertase .
C3 Convertase, Classical .
A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEMENT 3B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of COMPLEMENT 4B and COMPLEMENT 2A (C4b2a). .
0.68
03
 
Complement C5 Convertase, Classical Pathway .
C5 Convertase (C4b2a3b) .
Classical C5 Convertase .
Classical Pathway C5 Convertase .
C5 Convertase, Classical .
A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b. .
0.68
02
 
Complement C3-C5 Convertases, Classical Pathway .
Classical Pathway C3-C5 Convertases .
Classical Pathway C3 C5 Convertases .
Complement C3 C5 Convertases, Classical Pathway .
Important enzymes in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. They cleave COMPLEMENT C3 and COMPLEMENT C5. .
0.67
00
 
Complement C4b-Binding Protein .
C4b-Binding Protein .
C4b-C3b Inactivator Cofactor .
C4bC3bINA-Cofactor .
Complement 4b Binding Protein .
Complement C3b-C4b Inactivator Cofactor .
Complement Component 4b-Binding Protein .
C4b Binding Protein .
C4b C3b Inactivator Cofactor .
C4b-Binding Protein, Complement .
C4bC3bINA Cofactor .
Cofactor, C4b-C3b Inactivator .
Complement C3b C4b Inactivator Cofactor .
Complement C4b Binding Protein .
Complement Component 4b Binding Protein .
Protein, C4b-Binding .
Protein, Complement C4b-Binding .
A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a). .
0.65
0178