serw-MX  [xml]  
 


    
 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.024 Adaptor Proteins, Signal Transducing .
D12.644.360.024.131 CARD Signaling Adaptor Proteins .
D12.644.360.024.131.186 CRADD Signaling Adaptor Protein .
D12.644.360.024.131.249 Nod1 Signaling Adaptor Protein .
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins .
D12.644.360.024.285.050 CRADD Signaling Adaptor Protein .
D12.644.360.024.301 Insulin Receptor Substrate Proteins .
D12.644.360.024.313 Nod Signaling Adaptor Proteins .
D12.644.360.024.313.249 Nod1 Signaling Adaptor Protein .
D12.644.360.024.330 Shc Signaling Adaptor Proteins .
D12.644.360.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins .
D12.644.360.024.500.050 CRADD Signaling Adaptor Protein .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.358 CARD Signaling Adaptor Proteins .
D12.644.360.075.358.186 CRADD Signaling Adaptor Protein .
D12.644.360.075.358.249 Nod1 Signaling Adaptor Protein .
D12.644.360.075.421 Death Domain Receptor Signaling Adaptor Proteins .
D12.644.360.075.421.050 CRADD Signaling Adaptor Protein .
D12.644.360.539 NLR Proteins .
D12.644.360.539.500 Nod Signaling Adaptor Proteins .
D12.644.360.539.500.249 Nod1 Signaling Adaptor Protein .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.057 Adaptor Proteins, Signal Transducing .
D12.776.157.057.006 CARD Signaling Adaptor Proteins .
D12.776.157.057.006.186 CRADD Signaling Adaptor Protein .
D12.776.157.057.006.249 Nod1 Signaling Adaptor Protein .
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.157.057.018.050 CRADD Signaling Adaptor Protein .
D12.776.157.057.045 Insulin Receptor Substrate Proteins .
D12.776.157.057.078 Nod Signaling Adaptor Proteins .
D12.776.157.057.078.249 Nod1 Signaling Adaptor Protein .
D12.776.157.057.162 Shc Signaling Adaptor Proteins .
D12.776.157.057.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins .
D12.776.157.057.500.050 CRADD Signaling Adaptor Protein .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.024 Adaptor Proteins, Signal Transducing .
D12.776.476.024.139 CARD Signaling Adaptor Proteins .
D12.776.476.024.139.186 CRADD Signaling Adaptor Protein .
D12.776.476.024.139.249 Nod1 Signaling Adaptor Protein .
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.476.024.320.050 CRADD Signaling Adaptor Protein .
D12.776.476.024.382 Insulin Receptor Substrate Proteins .
D12.776.476.024.391 Nod Signaling Adaptor Proteins .
D12.776.476.024.391.249 Nod1 Signaling Adaptor Protein .
D12.776.476.024.424 Shc Signaling Adaptor Proteins .
D12.776.476.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins .
D12.776.476.024.500.050 CRADD Signaling Adaptor Protein .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.358 CARD Signaling Adaptor Proteins .
D12.776.476.075.358.186 CRADD Signaling Adaptor Protein .
D12.776.476.075.358.249 Nod1 Signaling Adaptor Protein .
D12.776.476.075.421 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.476.075.421.050 CRADD Signaling Adaptor Protein .
D12.776.543 Membrane Proteins .
D12.776.543.990 Vesicular Transport Proteins .
D12.776.543.990.150 Adaptor Proteins, Vesicular Transport .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Adaptor Proteins, Signal Transducing .
Signal Transducing Adaptor Proteins .
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes .
1.00
2327769
 
CARD Signaling Adaptor Proteins .
Caspase Activation and Recruitment Domain Signaling Proteins .
A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region. .
0.71
21164
 
Nod Signaling Adaptor Proteins .
NOD Leucine-Rich Repeat Proteins .
NOD-LRR Signaling Adaptor Proteins .
Nucleotide Oligomerization Domain Proteins .
NOD LRR Signaling Adaptor Proteins .
NOD Leucine Rich Repeat Proteins .
Nuclear Binding Oligomerization Domain Proteins .
Nuclear-Binding Oligomerization Domain Proteins .
Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance. .
0.69
3207
 
Death Domain Receptor Signaling Adaptor Proteins .
DED Signaling Adaptor Proteins .
DISC (Death Inducing Signaling Complex) .
Death Effector Domain Containing Proteins .
Death Effector Domain Signaling Adaptor Proteins .
Death Inducing Signaling Complex Proteins .
Fas-DISC Components .
fas Death-Inducing Signaling Complex Components .
Fas DISC Components .
fas Death Inducing Signaling Complex Components .
Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS. .
0.68
1431
 
Shc Signaling Adaptor Proteins .
Shc Adaptor Proteins .
Shc Family Adapter Proteins .
Adaptor Proteins, Shc .
A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this family are involved in transmitting signals from CELL SURFACE RECEPTORS to MITOGEN-ACTIVATED PROTEIN KINASES. .
0.67
11215
 
CRADD Signaling Adaptor Protein .
RIP-Associated Protein With a Death Domain .
RIP Associated Protein With a Death Domain .
Caspase and Rip Adaptor with Death Domain Protein .
RAIDD Signaling Adaptor Protein .
A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2. .
0.66
056
 
Adaptor Proteins, Vesicular Transport .
Adaptor Protein Complexes, Vesicular Transport .
Clathrin Adaptor Protein Complexes .
Clathrin Adaptors .
Clathrin Assembly Protein Complexes .
Clathrin-Associated Adaptors .
Clathrin-Associated Proteins .
Vesicular Transport Adaptor Protein Complexes .
Adaptors, Clathrin .
Adaptors, Clathrin-Associated .
Assembly Proteins, Clathrin .
Clathrin Associated Adaptors .
Clathrin Associated Proteins .
Clathrin Assembly Proteins .
Vesicular Transport Adaptor Proteins .
Adaptor Proteins .
A class of proteins involved in the transport of molecules via TRANSPORT VESICLES. They perform functions such as binding to the cell membrane, capturing cargo molecules and promoting the assembly of CLATHRIN. The majority of adaptor proteins exist as multi-subunit complexes, however monomeric varieties have also been found. .
0.66
33885
 
Insulin Receptor Substrate Proteins .
IRS Signaling Adaptor Proteins .
Insulin Receptor Substrate-1 .
Insulin Receptor Substrate-1 Protein .
Insulin Receptor Substrate-2 .
Insulin Receptor Substrate-2 Protein .
Insulin Receptor Substrate-3 .
Insulin Receptor Substrate-3 Protein .
Insulin Receptor Substrate-4 .
Insulin Receptor Substrate-4 Protein .
Insulin Receptor Substrate 1 .
Insulin Receptor Substrate 1 Protein .
Insulin Receptor Substrate 2 .
Insulin Receptor Substrate 2 Protein .
Insulin Receptor Substrate 3 .
Insulin Receptor Substrate 3 Protein .
Insulin Receptor Substrate 4 .
Insulin Receptor Substrate 4 Protein .
A structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR PROTEIN-TYROSINE KINASE. The proteins share an N-terminal PLECKSTRIN HOMOLOGY DOMAIN, a phosphotyrosine-binding domain that interacts with the phosphorylated INSULIN RECEPTOR, and a C-terminal TYROSINE-rich domain. Upon tyrosine phosphorylation, insulin receptor substrate proteins interact with specific SH2 DOMAIN containing proteins that are involved in insulin receptor signaling. .
0.66
 
Nod1 Signaling Adaptor Protein .
CARD4 Protein .
Caspase Recruitment Domain Protein 4 .
Nucleotide Oligomerization Domain 1 Protein .
A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM. .
0.65
2578