serw-MX  [xml]  
 


    
 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.395 Glycoproteins .
D12.776.395.550 Membrane Glycoproteins .
D12.776.395.550.200 Cell Adhesion Molecules .
D12.776.395.550.200.074 CD11 Antigens .
D12.776.395.550.200.074.500 CD11a Antigen .
D12.776.395.550.625 Platelet Membrane Glycoproteins .
D12.776.395.550.625.298 Integrin alpha2beta1 .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.200 Cell Adhesion Molecules .
D12.776.543.550.200.093 CD11 Antigens .
D12.776.543.550.200.093.500 CD11a Antigen .
D12.776.543.550.625 Platelet Membrane Glycoproteins .
D12.776.543.550.625.298 Integrin alpha2beta1 .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.685 Receptors, Collagen .
D12.776.543.750.685.100 Integrin alpha1beta1 .
D12.776.543.750.685.200 Integrin alpha2beta1 .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.408 Integrins .
D12.776.543.750.705.408.100 Integrin alpha Chains .
D12.776.543.750.705.408.100.100 CD11a Antigen .
D12.776.543.750.705.408.100.350 Integrin alpha2 .
D12.776.543.750.705.408.530 Receptors, Fibronectin .
D12.776.543.750.705.408.530.249 Integrin alpha2beta1 .
D12.776.543.750.705.408.850 Receptors, Very Late Antigen .
D12.776.543.750.705.408.850.099 Integrin alpha1beta1 .
D12.776.543.750.705.408.850.199 Integrin alpha2beta1 .
D12.776.543.750.705.675 Platelet Membrane Glycoproteins .
D12.776.543.750.705.675.352 Integrin alpha2beta1 .
D12.776.543.750.705.876 Receptors, Laminin .
D12.776.543.750.705.876.249 Integrin alpha1beta1 .
D12.776.543.750.705.876.280 Integrin alpha2beta1 .
D23 Biological Factors .
D23.050 Antigens .
D23.050.301 Antigens, Surface .
D23.050.301.350 Cell Adhesion Molecules .
D23.050.301.350.074 CD11 Antigens .
D23.050.301.350.074.024 CD11a Antigen .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Integrin alpha2beta1 .
CD49b-CD29 .
Glycoprotein Ia-IIa .
Platelet Membrane Glycoprotein Heterodimer Ia-IIa .
VLA-2 .
Very Late Antigen-2 .
alpha2beta1Integrin .
CD49b CD29 .
Glycoprotein Ia IIa .
Late Antigen-2, Very .
Platelet Membrane Glycoprotein Heterodimer Ia IIa .
VLA 2 .
Very Late Antigen 2 .
alpha2beta1, Integrin .
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase. .
1.00
1574
 
Integrin alpha2 .
CD49b Antigen .
GPIa 25162 .
Platelet Glycoprotein Ia .
VLA-2 alpha Chain .
alpha2 Integrin .
Antigen, CD49b .
Glycoprotein Ia, Platelet .
Integrin, alpha2 .
VLA 2 alpha Chain .
alpha Chain, VLA-2 .
alpha2, Integrin .
Antigens, CD49b .
CD49b Antigens .
An integrin alpha subunit that primarily combines with INTEGRIN BETA1 to form the INTEGRIN ALPHA2BETA1 heterodimer. It contains a domain which has homology to collagen-binding domains found in von Willebrand factor. .
0.82
0678
 
Integrin alpha Chains .
Integrin alpha Subunits .
Integrins, alpha .
alpha Chains, Integrin .
alpha Integrins .
The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4. .
0.76
11189
 
CD11a Antigen .
Integrin alphaL .
Antigen, CD11a .
alphaL, Integrin .
Antigens, CD11a .
CD11a Antigens .
An alpha-integrin subunit found on lymphocytes, granulocytes, macrophages and monocytes. It combines with the integrin beta2 subunit (CD18 ANTIGEN) to form LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1. .
0.75
0344
 
Integrin alpha1beta1 .
CD49a-CD29 .
Integrin alpha(1)beta(1) .
VLA-1 .
alpha1beta1 Integrin .
Integrin, alpha1beta1 .
alpha1beta1, Integrin .
Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29. .
0.75
0296