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 DeCS Categories

C10 Nervous System Diseases .
C10.574 Neurodegenerative Diseases .
C10.574.562 Motor Neuron Disease .
C10.668 Neuromuscular Diseases .
C10.668.467 Motor Neuron Disease .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Motor Neuron Disease .
Lower Motor Neuron Disease .
Motor Neuron Disease, Familial .
Motor Neuron Disease, Secondary .
Motor System Disease .
Primary Lateral Sclerosis .
Secondary Motor Neuron Disease .
Upper Motor Neuron Disease .
Lateral Scleroses .
Lateral Scleroses, Primary .
Lateral Sclerosis, Primary .
Motor Neuron Diseases .
Motor System Diseases .
Neuron Disease, Motor .
Neuron Diseases, Motor .
Primary Lateral Scleroses .
Scleroses, Lateral .
Scleroses, Primary Lateral .
Sclerosis, Lateral .
Sclerosis, Primary Lateral .
Lateral Sclerosis .
Anterior Horn Cell Disease .
Familial Motor Neuron Disease .
Motor Neuron Disease, Lower .
Motor Neuron Disease, Upper .
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) .
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