serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.005 Aryl Hydrocarbon Hydroxylases .
D08.244.453.005.500 Cytochrome P-450 CYP1B1 .
D08.244.453.012 Camphor 5-Monooxygenase .
D08.244.453.100 Cytochrome P450 Family 1 .
D08.244.453.100.875 Cytochrome P-450 CYP1B1 .
D08.244.453.484 Cytochrome P450 Family 11 .
D08.244.453.484.500 Cytochrome P-450 CYP11B2 .
D08.244.453.487 Cytochrome P450 Family 17 .
D08.244.453.487.500 Steroid 17-alpha-Hydroxylase .
D08.244.453.489 Cytochrome P450 Family 19 .
D08.244.453.489.500 Aromatase .
D08.244.453.498 Cytochrome P450 Family 26 .
D08.244.453.498.500 Retinoic Acid 4-Hydroxylase .
D08.244.453.915 Steroid Hydroxylases .
D08.244.453.915.050 Cytochrome P-450 CYP11B2 .
D08.244.453.915.099 Aromatase .
D08.244.453.915.748 Steroid 17-alpha-Hydroxylase .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.010 Aryl Hydrocarbon Hydroxylases .
D08.811.682.690.708.170.010.500 Cytochrome P-450 CYP1B1 .
D08.811.682.690.708.170.012 Camphor 5-Monooxygenase .
D08.811.682.690.708.170.020 Cytochrome P450 Family 1 .
D08.811.682.690.708.170.020.875 Cytochrome P-450 CYP1B1 .
D08.811.682.690.708.170.425 Cytochrome P450 Family 11 .
D08.811.682.690.708.170.425.500 Cytochrome P-450 CYP11B2 .
D08.811.682.690.708.170.444 Cytochrome P450 Family 17 .
D08.811.682.690.708.170.444.500 Steroid 17-alpha-Hydroxylase .
D08.811.682.690.708.170.447 Cytochrome P450 Family 19 .
D08.811.682.690.708.170.447.500 Aromatase .
D08.811.682.690.708.170.485 Cytochrome P450 Family 26 .
D08.811.682.690.708.170.485.500 Retinoic Acid 4-Hydroxylase .
D08.811.682.690.708.170.915 Steroid Hydroxylases .
D08.811.682.690.708.170.915.050 Cytochrome P-450 CYP11B2 .
D08.811.682.690.708.170.915.099 Aromatase .
D08.811.682.690.708.170.915.748 Steroid 17-alpha-Hydroxylase .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.010 Aryl Hydrocarbon Hydroxylases .
D12.776.422.220.453.010.500 Cytochrome P-450 CYP1B1 .
D12.776.422.220.453.012 Camphor 5-Monooxygenase .
D12.776.422.220.453.100 Cytochrome P450 Family 1 .
D12.776.422.220.453.100.875 Cytochrome P-450 CYP1B1 .
D12.776.422.220.453.484 Cytochrome P450 Family 11 .
D12.776.422.220.453.484.500 Cytochrome P-450 CYP11B2 .
D12.776.422.220.453.487 Cytochrome P450 Family 17 .
D12.776.422.220.453.487.500 Steroid 17-alpha-Hydroxylase .
D12.776.422.220.453.489 Cytochrome P450 Family 19 .
D12.776.422.220.453.489.500 Aromatase .
D12.776.422.220.453.498 Cytochrome P450 Family 26 .
D12.776.422.220.453.498.500 Retinoic Acid 4-Hydroxylase .
D12.776.422.220.453.915 Steroid Hydroxylases .
D12.776.422.220.453.915.050 Cytochrome P-450 CYP11B2 .
D12.776.422.220.453.915.099 Aromatase .
D12.776.422.220.453.915.748 Steroid 17-alpha-Hydroxylase .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Retinoic Acid 4-Hydroxylase .
CYP26A1 .
CYP26A1 Enzyme .
CYP26B1 .
CYP450 4-Hydroxylase .
Cytochrome P-450 26B1 .
Cytochrome P-450 CYP26B1 .
Cytochrome P450 26A1 Enzyme .
Cytochrome P450 4-Hydroxylase .
P450RAI .
RA-4-Hydroxylase .
Retinoic Acid-Metabolizing Enzyme, CYP26B1 .
CYP26B1, Cytochrome P-450 .
Cytochrome P 450 CYP26B1 .
Cytochrome P450 4 Hydroxylase .
Enzyme, CYP26A1 .
RA 4 Hydroxylase .
Retinoic Acid 4 Hydroxylase .
Retinoic Acid Metabolizing Enzyme, CYP26B1 .
A cytochrome P450 enzyme that resides in the ENDOPLASMIC RETICULUM. It catalyzes the conversion of trans-RETINOIC ACID to 4-hydroxyretinoic acid. .
1.00
0417
 
Camphor 5-Monooxygenase .
CYP101 .
Camphor-5-Monooxygenase .
Cytochrome P-450 101 .
Cytochrome P-450-cam .
Cytochrome P450(cam) .
P450cam .
Camphor 5 Monooxygenase .
Cytochrome P 450 101 .
Cytochrome P 450 cam .
Cytochrome P-450(cam) .
A soluble cytochrome P-450 enzyme that catalyzes camphor monooxygenation in the presence of putidaredoxin, putidaredoxin reductase, and molecular oxygen. This enzyme, encoded by the CAMC gene also known as CYP101, has been crystallized from bacteria and the structure is well defined. Under anaerobic conditions, this enzyme reduces the polyhalogenated compounds bound at the camphor-binding site. .
0.53
0429
 
Aromatase .
Androstenedione Aromatase .
CYP 19 .
CYP19 Protein .
Cytochrome P450 19 .
Estrogen Synthase .
Estrogen Synthetase .
P450AROM .
Aromatase, Androstenedione .
Cytochrome P 450 CYP19 .
Protein, CYP19 .
Cytochrome P-450(AROM) .
Cytochrome P-450 CYP19 .
CYP19 .
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system. .
0.52
455736
 
Cytochrome P-450 Enzyme System .
CYP450 Family .
CYP450 Superfamily .
Cytochrome P-450 Enzymes .
Cytochrome P-450 Families .
Cytochrome P-450 Monooxygenase .
Cytochrome P-450 Oxygenase .
Cytochrome P-450 Superfamily .
Cytochrome P450 .
Cytochrome P450 Superfamily .
Cytochrome p450 Families .
P-450 Enzymes .
P450 Enzymes .
Cytochrome P 450 .
Cytochrome P 450 Dependent Monooxygenase .
Cytochrome P 450 Enzyme System .
Cytochrome P 450 Enzymes .
Cytochrome P 450 Families .
Cytochrome P 450 Monooxygenase .
Cytochrome P 450 Oxygenase .
Cytochrome P 450 Superfamily .
Enzymes, Cytochrome P-450 .
Enzymes, P-450 .
Enzymes, P450 .
Monooxygenase, Cytochrome P-450 .
Monooxygenase, Cytochrome P-450-Dependent .
P 450 Enzymes .
P-450 Enzymes, Cytochrome .
Superfamily, CYP450 .
Superfamily, Cytochrome P-450 .
Superfamily, Cytochrome P450 .
Cytochrome P-450 .
Cytochrome P-450-Dependent Monooxygenase .
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. .
0.48
4439776
 
Steroid 17-alpha-Hydroxylase .
17 alpha-Hydroxylase Cytochrome P-450 .
17 alpha-Hydroxyprogesterone Aldolase .
17,20-Desmolase .
Cytochrome P-450(17-alpha) .
Cytochrome P450(17 alpha) .
Hydroxyprogesterone Aldolase .
Steroid 17 alpha-Hydroxylase .
Steroid-17-Hydroxylase .
17 alpha Hydroxylase .
17 alpha Hydroxylase Cytochrome P 450 .
17 alpha Hydroxyprogesterone Aldolase .
17 alpha-Hydroxylase, Steroid .
17 alpha-Monooxygenase, Steroid .
17,20 Desmolase .
17,20 Lyase .
17-Hydroxylase, Steroid .
17-Monooxygenase, Steroid .
17-alpha-Hydroxylase, Steroid .
Aldolase, 17 alpha-Hydroxyprogesterone .
Aldolase, Hydroxyprogesterone .
Steroid 17 Hydroxylase .
Steroid 17 Monooxygenase .
Steroid 17 alpha Hydroxylase .
Steroid 17 alpha Monooxygenase .
alpha-Hydroxyprogesterone Aldolase, 17 .
alpha-Monooxygenase, Steroid 17 .
17 alpha-Hydroxylase .
17,20-Lyase .
CYP17 .
Cytochrome P-450(17 alpha) .
P450(c17) .
Steroid 17 alpha-Monooxygenase .
Steroid 17-Hydroxylase .
Steroid 17-Monooxygenase .
17 ALPHA-HYDROXYPROGESTERONE ALDOLASE .
A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation. .
0.48
72446
 
Cytochrome P-450 CYP11B2 .
Aldosterone Synthase Cytochrome P-450 .
Aldosynthase .
CYP 11B2 .
Cytochrome P-450c11AS .
Cytochrome P450 11B2 .
Cytochrome P450Aldo .
P450c11AS .
Cytochrome P 450 CYP11B2 .
Cytochrome P 450c11AS .
Steroid 18 Hydroxylase .
CYP11B2 .
Aldosterone Synthase .
Steroid 18-Hydroxylase .
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE. .
0.45
51028
 
Cytochrome P-450 CYP1B1 .
Cytochrome P450 CYP1B1 .
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 .
Cytochrome P4501B1 .
Cytochrome P 450 CYP1B1 .
P450 CYP1B1, Cytochrome .
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly. .
0.39
01354