serw-MX  [xml]  

 DeCS Categories

D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.129 Azoles .
D03.383.129.308 Imidazoles .
D03.383.129.308.030 Aminoimidazole Carboxamide .
D09 Carbohydrates .
D09.408 Glycosides .
D09.408.620 Nucleotides .
D13 Nucleic Acids, Nucleotides, and Nucleosides .
D13.444 Nucleic Acids .
D13.444.600 Nucleic Acid Probes .
D13.444.600.601 Oligonucleotide Probes .
D13.695 Nucleotides .
D13.695.250 Dinucleoside Phosphates .
D13.695.578 Polynucleotides .
D13.695.578.424 Oligonucleotides .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.259 Diagnostic Uses of Chemicals .
D27.505.259.750 Molecular Probes .
D27.505.259.750.600 Nucleic Acid Probes .
D27.505.259.750.600.650 Oligonucleotide Probes .
D27.720 Specialty Uses of Chemicals .
D27.720.470 Laboratory Chemicals .
D27.720.470.530 Molecular Probes .
D27.720.470.530.600 Nucleic Acid Probes .
D27.720.470.530.600.650 Oligonucleotide Probes .
E05 Investigative Techniques .
E05.393 Genetic Techniques .
E05.393.183 Chromosome Mapping .
E05.393.183.250 Chromosome Walking .
G05 Genetic Phenomena .
G05.365 Genetic Variation .
G05.365.795 Polymorphism, Genetic .
 Synonyms & Historicals
Oligonucleotides .
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed) .
Oligonucleotide Probes .
Probes, Oligodeoxyribonucleotide .
Probes, Oligonucleotide .
Probes, Oligoribonucleotide .
Oligodeoxyribonucleotide Probes .
Oligoribonucleotide Probes .
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin. .
Aminoimidazole Carboxamide .
Ba 2756 .
Carboxamide, Aminoimidazole .
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases. .
Nucleotides .
The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed) .
Polymorphism, Genetic .
Genetic Polymorphisms .
Polymorphisms (Genetics) .
Polymorphisms, Genetic .
Polymorphism (Genetics) .
Genetic Polymorphism .
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level. .
Dinucleoside Phosphates .
Bis(5'-Nucleosidyl)Tetraphosphate .
Dinucleoside Polyphosphates .
Diphosphates, Dinucleoside .
Monophosphates, Dinucleoside .
Oligophosphates, Dinucleoside .
Phosphates, Deoxydinucleoside .
Phosphates, Dinucleoside .
Polyphosphates, Dinucleoside .
Tetraphosphates, Dinucleoside .
Triphosphates, Dinucleoside .
Bis(5'-Nucleosidyl)Oligophosphates .
Bis(5'-Nucleosidyl)Phosphates .
Deoxydinucleoside Phosphates .
Dinucleoside Diphosphates .
Dinucleoside Monophosphates .
Dinucleoside Oligophosphates .
Dinucleoside Tetraphosphates .
Dinucleoside Triphosphates .
A group of compounds which consist of a nucleotide molecule to which an additional nucleoside is attached through the phosphate molecule(s). The nucleotide can contain any number of phosphates. .
Chromosome Walking .
Chromosome Walkings .
Walking, Chromosome .
Walkings, Chromosome .
A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome. .