serw-MX  [xml]  

 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.776 Proteins .
D12.776.467 Intercellular Signaling Peptides and Proteins .
D12.776.467.150 B7 Antigens .
D12.776.467.150.300 B7-H1 Antigen .
D12.776.467.150.800 Programmed Cell Death 1 Ligand 2 Protein .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.095 B7 Antigens .
D12.776.543.095.300 B7-H1 Antigen .
D12.776.543.095.800 Programmed Cell Death 1 Ligand 2 Protein .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.222 Costimulatory and Inhibitory T-Cell Receptors .
D12.776.543.750.705.222.875 Programmed Cell Death 1 Receptor .
D23 Biological Factors .
D23.050 Antigens .
D23.050.301 Antigens, Surface .
D23.050.301.264 Antigens, Differentiation .
D23.050.301.264.894 Antigens, Differentiation, T-Lymphocyte .
D23.050.301.264.894.790 Programmed Cell Death 1 Receptor .
D23.050.301.285 B7 Antigens .
D23.050.301.285.400 B7-H1 Antigen .
D23.050.301.285.800 Programmed Cell Death 1 Ligand 2 Protein .
D23.101 Biomarkers .
D23.101.100 Antigens, Differentiation .
D23.101.100.894 Antigens, Differentiation, T-Lymphocyte .
D23.101.100.894.790 Programmed Cell Death 1 Receptor .
D23.529 Intercellular Signaling Peptides and Proteins .
D23.529.168 B7 Antigens .
D23.529.168.300 B7-H1 Antigen .
D23.529.168.800 Programmed Cell Death 1 Ligand 2 Protein .
G04 Cell Physiological Phenomena .
G04.146 Cell Death .
G04.146.160 Apoptosis .
G04.146.399 Autophagy .
G04.417 Endocytosis .
G04.417.350 Phagocytosis .
G04.417.350.091 Autophagy .
 Synonyms & Historicals
Programmed Cell Death 1 Ligand 2 Protein .
Antigens, CD273 .
B7-DC Antigen .
B7-DC Ligand .
CD273 Antigen .
PD-L2 Ligand .
Antigen, B7-DC .
Antigen, CD273 .
B7 DC Antigen .
B7 DC Ligand .
CD273 Antigens .
Ligand, B7-DC .
Ligand, PD-L2 .
PD L2 Ligand .
A costimulatory B7 antigen that has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 RECEPTOR. It is closely-related to CD274 antigen; however, its expression is restricted to DENDRITIC CELLS and activated MACROPHAGES. .
B7-H1 Antigen .
B7-H1 Immune Costimulatory Protein .
B7H1 Immune Costimulatory Protein .
CD274 Antigen .
PD-L1 Costimulatory Protein .
Programmed Cell Death 1 Ligand 1 .
Antigen, B7-H1 .
Antigen, CD274 .
B7 H1 Antigen .
B7 H1 Immune Costimulatory Protein .
CD274 Antigens .
Costimulatory Protein, PD-L1 .
PD L1 Costimulatory Protein .
Programmed Cell Death 1 Ligand 1 Protein .
Antigens, CD274 .
An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION. .
Programmed Cell Death 1 Receptor .
Antigens, CD279 .
CD279 Antigen .
PD-1 Receptor .
PD1 Receptor .
Antigen, CD279 .
CD279 Antigens .
PD 1 Receptor .
Receptor, PD-1 .
Receptor, PD1 .
Programmed Cell Death 1 Protein .
An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE. .
Apoptosis Regulatory Proteins .
Apoptosis Inducing Proteins .
Apoptosis Inhibiting Proteins .
Death Factors (Apoptosis) .
Programmed Cell Death Proteins .
Survival Factors (Apoptosis) .
Regulatory Proteins, Apoptosis .
Anti-Apoptotic Proteins .
Pro-Apoptotic Proteins .
A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES. .
Apoptosis .
Apoptosis, Extrinsic Pathway .
Apoptosis, Intrinsic Pathway .
Programmed Cell Death, Type I .
Apoptoses, Extrinsic Pathway .
Apoptoses, Intrinsic Pathway .
Extrinsic Pathway Apoptoses .
Extrinsic Pathway Apoptosis .
Intrinsic Pathway Apoptoses .
Intrinsic Pathway Apoptosis .
Cell Death, Programmed .
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. .
Autophagy .
Autophagic Cell Death .
Autophagic Programmed Cell Death .
Autophagy, Cellular .
Macro-autophagy .
Macroautophagy .
Programmed Cell Death, Type II .
Autophagic Cell Deaths .
Autophagies .
Autophagies, Cellular .
Cell Death, Autophagic .
Cell Deaths, Autophagic .
Cellular Autophagies .
Cellular Autophagy .
Death, Autophagic Cell .
Deaths, Autophagic Cell .
Macro autophagy .
Macro-autophagies .
Macroautophagies .
Autophagocytosis .
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer. .