serw-MX  [xml]  

 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.395 Glycoproteins .
D12.776.395.550 Membrane Glycoproteins .
D12.776.395.550.625 Platelet Membrane Glycoproteins .
D12.776.395.550.625.298 Integrin alpha2beta1 .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.625 Platelet Membrane Glycoproteins .
D12.776.543.550.625.298 Integrin alpha2beta1 .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.685 Receptors, Collagen .
D12.776.543.750.685.100 Integrin alpha1beta1 .
D12.776.543.750.685.200 Integrin alpha2beta1 .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.408 Integrins .
D12.776.543.750.705.408.100 Integrin alpha Chains .
D12.776.543.750.705.408.100.350 Integrin alpha2 .
D12.776.543.750.705.408.530 Receptors, Fibronectin .
D12.776.543.750.705.408.530.249 Integrin alpha2beta1 .
D12.776.543.750.705.408.850 Receptors, Very Late Antigen .
D12.776.543.750.705.408.850.099 Integrin alpha1beta1 .
D12.776.543.750.705.408.850.199 Integrin alpha2beta1 .
D12.776.543.750.705.675 Platelet Membrane Glycoproteins .
D12.776.543.750.705.675.352 Integrin alpha2beta1 .
D12.776.543.750.705.876 Receptors, Laminin .
D12.776.543.750.705.876.249 Integrin alpha1beta1 .
D12.776.543.750.705.876.280 Integrin alpha2beta1 .
 Synonyms & Historicals
Integrin alpha2beta1 .
CD49b-CD29 .
Glycoprotein Ia-IIa .
Platelet Membrane Glycoprotein Heterodimer Ia-IIa .
VLA-2 .
Very Late Antigen-2 .
alpha2beta1Integrin .
CD49b CD29 .
Glycoprotein Ia IIa .
Late Antigen-2, Very .
Platelet Membrane Glycoprotein Heterodimer Ia IIa .
VLA 2 .
Very Late Antigen 2 .
alpha2beta1, Integrin .
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase. .
Integrin alpha2 .
CD49b Antigen .
GPIa 25162 .
Platelet Glycoprotein Ia .
VLA-2 alpha Chain .
alpha2 Integrin .
Antigen, CD49b .
Glycoprotein Ia, Platelet .
Integrin, alpha2 .
VLA 2 alpha Chain .
alpha Chain, VLA-2 .
alpha2, Integrin .
Antigens, CD49b .
CD49b Antigens .
An integrin alpha subunit that primarily combines with INTEGRIN BETA1 to form the INTEGRIN ALPHA2BETA1 heterodimer. It contains a domain which has homology to collagen-binding domains found in von Willebrand factor. .
Integrin alpha1beta1 .
CD49a-CD29 .
Integrin alpha(1)beta(1) .
VLA-1 .
alpha1beta1 Integrin .
Integrin, alpha1beta1 .
alpha1beta1, Integrin .
Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29. .