serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.037 Deubiquitinating Enzymes .
D08.811.037.500 Ubiquitin Thiolesterase .
D08.811.277 Hydrolases .
D08.811.277.352 Esterases .
D08.811.277.352.897 Thiolester Hydrolases .
D08.811.277.352.897.850 Ubiquitin Thiolesterase .
D08.811.277.785 Protein Deglycase DJ-1 .
D08.811.399 Isomerases .
D08.811.399.403 DNA Topoisomerases .
D08.811.399.403.741 DNA Topoisomerases, Type II .
D08.811.399.403.741.224 DNA Topoisomerase IV .
D08.811.913 Transferases .
D08.811.913.400 Glycosyltransferases .
D08.811.913.400.725 Pentosyltransferases .
D08.811.913.400.725.115 ADP Ribose Transferases .
D08.811.913.400.725.115.690 Poly(ADP-ribose) Polymerases .
D08.811.913.400.725.115.690.420 Poly (ADP-Ribose) Polymerase-1 .
D08.811.913.696 Phosphotransferases .
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) .
D08.811.913.696.620.682 Protein Kinases .
D08.811.913.696.620.682.700 Protein-Serine-Threonine Kinases .
D08.811.913.696.620.682.700.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.097 Bacterial Proteins .
D12.776.097.256 DNA Topoisomerase IV .
D12.776.124 Blood Proteins .
D12.776.124.486 Immunoproteins .
D12.776.124.486.485 Immunoglobulins .
D12.776.124.486.485.900 Paraproteins .
D12.776.124.790 Serum Globulins .
D12.776.124.790.651 Immunoglobulins .
D12.776.124.790.651.900 Paraproteins .
D12.776.377 Globulins .
D12.776.377.715 Serum Globulins .
D12.776.377.715.548 Immunoglobulins .
D12.776.377.715.548.900 Paraproteins .
D12.776.637 Parkinson Disease Associated Proteins .
D12.776.637.750 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 .
D12.776.637.875 Protein Deglycase DJ-1 .
D12.776.637.937 Ubiquitin Thiolesterase .
SP4 Environmental Health .
SP4.011 Science .
SP4.011.097 Chemistry .
SP4.011.097.036 Organic Chemicals .
SP4.011.097.036.694 Proteins .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
DNA Topoisomerase IV .
Topo IV .
Topoisomerase IV .
Topoisomerase IV Subunit A .
Topoisomerase IV Subunit B .
parC Gene Product .
parC Gene Product, Topo IV .
parE Gene Product .
parE Gene Product, Topo IV .
Topoisomerase IV, DNA .
parC Protein .
parE Protein .
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. .
1.00
 
Parkinson Disease Associated Proteins .
PARK Proteins .
Parkinson Associated Proteins .
Associated Proteins, Parkinson .
Proteins, PARK .
Proteins, Parkinson Associated .
Proteins associated with sporadic or familial cases of PARKINSON DISEASE. .
0.87
12
 
Protein Deglycase DJ-1 .
DJ-1 Protein .
DJ-1-PARK7 Protein .
DJ1 Protein .
PARK7 Protein .
Parkinson Protein 7 .
Parkinsonism Associated Deglycase .
DJ 1 PARK7 Protein .
DJ 1 Protein .
DJ-1, Protein Deglycase .
Deglycase, Parkinsonism Associated .
A protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, releasing repaired proteins and lactate or glycolate. It deglycates CYSTEINE, ARGININE and LYSINE residues to reactivate proteins by reversing glycation and prevent the formation of ADVANCED GLYCATION END PRODUCTS. It protects cells against OXIDATIVE STRESS and CELL DEATH by functioning as an oxidative stress sensor and redox-sensitive MOLECULAR CHAPERONE and PROTEASE. Mutations in the PARK7 gene are associated with autosomal-recessive, early-onset PARKINSON DISEASE. .
0.80
0776
 
Ubiquitin Thiolesterase .
Neuron Cytoplasmic Protein 9.5 .
PARK5 Protein .
Parkinson Disease 5 Protein .
UCHL1 Protein .
Ubiquitin C-Terminal Esterase .
Ubiquitin C-Terminal Hydrolase .
Ubiquitin Carboxy-Terminal Esterase .
Ubiquitin Carboxy-Terminal Hydrolase .
Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 .
Uch-L1 Protein .
C-Terminal Esterase, Ubiquitin .
C-Terminal Hydrolase, Ubiquitin .
Carboxy-Terminal Esterase, Ubiquitin .
Carboxy-Terminal Hydrolase, Ubiquitin .
Esterase, Ubiquitin C-Terminal .
Esterase, Ubiquitin Carboxy-Terminal .
Hydrolase, Ubiquitin C-Terminal .
Hydrolase, Ubiquitin Carboxy-Terminal .
Thiolesterase, Ubiquitin .
Ubiquitin C Terminal Esterase .
Ubiquitin C Terminal Hydrolase .
Ubiquitin Carboxy Terminal Esterase .
Ubiquitin Carboxy Terminal Hydrolase .
Ubiquitin Carboxyl Terminal Hydrolase Isozyme L1 .
Uch L1 Protein .
A thioester hydrolase which acts on esters formed between thiols such as DITHIOTHREITOL or GLUTATHIONE and the C-terminal glycine residue of UBIQUITIN. .
0.80
53037
 
Poly (ADP-Ribose) Polymerase-1 .
NAD+ ADP-ribosyltransferase-1 .
PARP-1 Protein .
PARP1 Protein .
Poly (ADP-Ribose) Synthase-1 .
NAD+ ADP ribosyltransferase 1 .
PARP 1 Protein .
A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE. .
0.80
42210
 
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 .
Dardarin Protein .
LRRK2 Protein .
PARK8 Protein .
Leucine Rich Repeat Serine Threonine Protein Kinase 2 .
A serine/threonine protein kinase with GTPase activity that contains 12 LEUCINE-rich repeats in its central region and 7 WD repeats C-terminal to its kinase and GTPase domains. It localizes to TRANSPORT VESICLES; the OUTER MITOCHONDRIAL MEMBRANE; and the GOLGI APPARATUS. It functions in PROTEIN TRANSPORT; regulates neuron morphology in the central nervous system, and also functions in the trafficking of SYNAPTIC VESICLES. Mutations in the LRRK2 gene have been identified in autosomal dominant cases of PARKINSON DISEASE (PARK8). .
0.80
01228
 
Proteins .
Protein Gene Products .
Proteins, Gene .
Gene Proteins .
Gene Products, Protein .
GENE PRODUCTS .
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. .
0.67
978177635
 
Paraproteins .
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered. .
0.65
18817